Nutraceutical proteins and peptides in health and disease

Title: Early Nutrition and Its Later Consequences: New Opportunities: Perinatal Programming of Adult Health - EC Supported Research
Editors: Berthold Koletzko, Peter Dodds , Hans Akerblom
Publisher: Springer
Publication Date: 2005-05-01
Number Of Pages: 256
ISBN: 1402035349
ISBN-13: 978-1402035340

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Book Description

Health problems such as hypertension, tendency to diabetes, obesity, blood lipids, vascular disease, bone health, behaviour and learning and longevity may be imprinted during early life. This process is defined as programming whereby a nutritional stimulus operating at a critical, sensitive period of pre and postnatal life imprints permanent effects on the structure, physiology and metabolism.

For this reason, academics and industry set-up the EC supported Scientific Workshop -Early Nutrition and its Later Consequences: New Opportunities. The prime objective of the Workshop was to generate a sound exchange of the latest scientific developments within the field of early nutrition to look for opportunities for new preventive health concepts. Further, a closer look was taken at the development of food applications which could provide (future) mothers and infants with improved nutrition that will ultimately lead to better future health. The Workshop was organised by the Dept. of Pediatrics, University of Munich, Germany in collaboration with the Danone Institutes and the Infant Nutrition Cluster, a collaboration of three large research projects funded by the EU.

Table of Contents

Preface : what is the EU infant nutrition cluster?
Early nutrition and its later consequences : new opportunities 1
The developmental origins of adult health and well-being 13
Long term effects of breastfeeding on the infant and mother 16
Experimental evidence for long-term programming effects of early diet 24
Candidate genes for obesity - how might they interact with environment and diet? 33
Rate of growth in early life : a predictor of later health? 35
Protective effect of breast-feeding against obesity in childhood 40
Discussion forum : from innovation to implementation 49
Challenges and opportunities in pan-European collaboration for researchers from Central and Eastern Europe 54
Best practice in communicating the results of European research to the public 60
Longterm effects of pre- and postnatal exposure to low and high dietary protein levels 64
Protein intake in the first year of life : a risk factor for later obesity? 69
The role of long-chain poly-unsaturated fatty acids (LCPUFA) in growth and development 80
Experimental models for studying perinatal lipid metabolism 95
Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy : the Nuheal trial 109
Young researchers' workshop 114
Consumer needs regarding dietetic products for pregnant and lactating women and for baby foods 120
Focus group : breakfast meeting : SMES and their co-operation with academia 127
Ethical issues in perinatal nutrition research 132
Early programming of diabetes risk - an introduction 139
Early nutrition and later diabetes risk 142
Is type 1 diabetes a disease of the gut immune system triggered by cow's milk insulin? 151
Gluten-free diet in subjects at risk for type 1 diabetes : a tool for delaying progression to clinical disease? 157
Insulin like growth factor regulation of body mass in breastfed and milk formula fed infants
Inverse association between trans isomeric and long-chain polyunsaturated fatty acids in erythrocyte membrane lipids in pregnant women 164
Comparison of essential fatty acid status among German, Hungarian and Spanish women at mid-gestation 166
Trans isomeric fatty acids as confounding variables in studies on perinatal LC-PUFA supply 168
An eight years prospective study of iron deficiency anaemia in infancy 170
New insights in the potential mechanism of action of nucleotides to modulate immunity 172
Thriving of malnourished breastfed infants after additional formula milk feeding 174
Role of mammary gland lipoprotein lipase in the availability of polyunsaturated fatty acids for milk synthesis 176
Is the crying behaviour in infants up to the age of 3 months influenced by the type of early nutrition? 177
Dietary gangliosides : beneficial effects for the neonate and potential mechanism of action 179
Leptin in breast-fed and formula-fed infants 181
Dietary fatty acids during pregnancy determines maternal fatty acid profile during late pregnancy and their availability to the fetus even during fasting conditions 183
Effect of oil-supplemented diets on liver expression of PPAR alpha-related genes in pregnant rats 185
Effect of a new infant formula enriched with prebiotics, probiotics, nucleotides and LC-PUFA on recovery after infection 186
Does habitual protein intake in early childhood influence age and body mass index at adiposity rebound? 188
Dietary compliance in diabetes prevention project in Finland 189
Changes of plasma fatty acid profile and antioxidant vitamins during normal pregnancy 190
Optimal design for the recruitment of participants as a factor for the effective implementation of a clinical trial 191
The effect of ponderal index on plasma concentration of insulin-like growth factor-1 (IGF-1) in neonatal pigs 193
Effects of prenatal exposure to low and high dietary protein levels on maternal and fetal amino acid metabolism in rats 195
Cow's milk introduction in Spanish infants 196
Longer term effects of early cholesterol intake on cholesterol biosynthesis and plasma lipids : a randomized clinical trial 197
Patterns of growth and energy utilization of the diet after a period of dietary restriction during the weaning period 198
Infant formula feeding pattern and weaning introduction in Spanish infants 199
Visual evoked potentials in infants after dietary supply of docosahexaenoic acid and 5-methyltetrahydrofolate during pregnancy 201
Electronic data capture and use of Internet technologies in a double-blind randomised intervention trial 203
Breastfeeding and baby friendly hospital initiative in Slovenia 205
Nutritional status in young adults with screen-detected silent/sub-clinical coeliac disease 207
Lipoprotein lipase (LPL) MRNA expression in placentas from normal and IUGR (intrauterine growth restricted) pregnancies by real-time PCR 208
Maternal fasting effect on neonatal health 210
The quality of schoolchildren's nutrition in Serbia 212
Tendency towards obesity in sydney school children 214
Monitoring and supervising a dietary intervention trial using modern data processing system 216
Analysis of drop-outs in a longitudinal study 217
Recruitment strategies of the Spanish group in the "EU childhood obesity : programming by infant nutrition" 218
Diet and nutritional risk factors in schoolchildren 219
Influence of two forms of caseinophosphopeptide on iron bio availability 221
Model of childhood obesity primary prevention programme 223
Problems related to recruitment of participants for the Triger project 225
Vitamin D status at birth in Brussels - preliminary results 226
Obesity among young adolescent Kuwaitis 228
Dynamic changes in adiposity from fetal to postnatal life are involved in the adult metabolic syndrome associated with reduced fetal growth 229
Excess fetal adiposity is associated with programming of placental lipid genes 231
Appetite control in breastfed and formula fed infants
What are the Danone Institutes 235

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