Cancer Immunotherapy: Immune Suppression and Tumor Growth

Cancer Immunotherapy: Immune Suppression and Tumor Growth

Product Details
Book Publisher: Academic Press (01 June, 2007)
ISBN: 0123725518
Book author: George C. Prendergast, Elizabeth M. Jaffee
Amazon Rating: 5.0

Book Description:
There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumoral immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease.

* Offers a synthesis of concepts that are useful to cancer immunologists and pharmacologists, who tend to work in disparate fields with little cross-communication
* Drs Prendergast and Jaffee are internationally recognized leaders in cancer biology and immunology who have created a unique synthesis of fundamental and applied concepts in this important new area of cancer research
* Summarizes the latest insights into how immune escape defines an essential trait of cancer
* Includes numerous illustrations including: how molecular-targeted therapeutic drugs or traditional chemotherapy can be combined with immunotherapy to improve anti-tumor efficacy; and how reversing immune suppression by the tumor can cause tumor regression

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Advances in Multiple Sclerosis and Experimental Demyelinating Diseases

Advances in Multiple Sclerosis and Experimental Demyelinating Diseases (Current Topics in Microbiology and Immunology) (Current Topics in Microbiology and Immunology)
By Moses Rodriguez

• Publisher: Springer


• Number Of Pages: 362


• Publication Date: 2007-12-18


• ISBN-10 / ASIN: 354073676X


• ISBN-13 / EAN: 9783540736769


• Binding: Hardcover

Product Description:


There is a need for a paradigm shift in our thinking about the pathogenesis of multiple sclerosis.
Challenging Charcot s hypothesis that inflammatory response is the primary contributor to demyelination, Dr. Rodriguez and colleagues take a fresh, bold look at the causes and possible treatments of MS.
Assuming oligodendrocyte injury as a prerequisite to MS, the authors explore viruses, toxins and genetic defects as possible culprits. They present novel methods to interrupt and reverse demyelination. This book examines the correlation between axonal loss and clinical deficits, including the implied role of the CD8+ T cell and perforin. It assesses proteases, specifically, kallikrein 6, which are strongly associated with active demyelination. By directing natural autoantibodies against oligodendrocytes that demonstrate remyelination in animal models, the authors envision clinical trials for remyelination enhancement.
As internationally recognized specialists in a wide range of MS disciplines, the authors explore genetic tools for identifying patients who are most likely to experience spontaneous remyelination. Epidemiology studies offer additional avenues of treatment. Examples include uric acid, statin drugs, estrogen and progesterone.
MS affects nearly 400,000 people in the United States, many of whom are between18 and 40 years of age. With their novel, multifaceted approach to basic science and their applications in understanding cause and treatment the authors offer help to clinicians and hope to patients.

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Human Antibody Therapeutics For Viral Disease

Human Antibody Therapeutics For Viral Disease (Current Topics in Microbiology and Immunology)
By Scott K. Dessain
Publisher: Springer
Number Of Pages: 190
Publication Date: 2007-12-06
ISBN-10 / ASIN: 3540721444
ISBN-13 / EAN: 9783540721444
Binding: Hardcover

Although the utility of human antibodies as medical therapeutics for cancer and immune diseases has been well-established, it is only beginning to be realized for the treatment of viral infectious diseases. Polyclonal immunoglobulins have long been used for some viral diseases, but they have limited potency and disease scope. It should theoretically be possible to create monoclonal or oligoclonal antibody preparations that capture the essential curative functions of the humoral immune response to viral pathogens, yet only a single humanized monoclonal antibody (pavilizumab) has been approved as a viral countermeasure. Reliable technologies for creating human or humanized antibodies with defined viral antigen specificities are well-established. Accordingly, current antibody development efforts are focused on identifying and cloning the particular antibodies that contain the fundamental curative potency of the polyclonal humoral immune response

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Fungal Immunology:: From an Organ Perspective

Fungal Immunology:: From an Organ Perspective

Product Details
Book Publisher: Springer (06 June, 2005)
ISBN: 0387240926
Book author: Jr., Paul L. Fidel, Gary B. Huffnagle
Amazon Rating:

Book Description:
Fungal immunology, an expanding field of research, studies the interaction between fungi and the immune system. Modulated immunity as well as evasive mechanisms played by fungi all contribute to the chronicity and reoccurrence of fungal infections. Hypersensitivity to various fungal elements plays a major role in the pathogenesis of many diseases. This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by organ system. All other texts in the field, which are now quite old, are arranged according to specific fungi. Organization by body system rather than fungi is important because one particular fungus can have a different effect on defense mechanisms in different parts of the body.

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Immunology of Fungal Infections

Immunology of Fungal Infections

Product Details
Book Publisher: Springer (January, 2007)
ISBN: 1402054912
Book author: Gordon D. Brown, Mihai G. Netea
Amazon Rating:

Book Description:

The immunology of fungal infections is a comprehensive text covering all aspects of the immunology of infection with fungal pathogens. In addition to established knowledge, this book covers recent developments in the innate and adaptive immunological mechanisms involved in the host response to fungal infection.

The volume is divided into a number of sections, which provide an immunological perspective on the cells, soluble factors and receptors involved in recognising and combating fungal pathogens. Further sections provide detailed descriptions of immunity to specific fungi, immune-escape mechanisms used by these organisms and immune-based therapeutic strategies.

This book would be a valuable resource for those interested in fungal immunology particularly, students, specialists, teachers, researchers and clinicians.

Product Details

* Hardcover: 500 pages
* Publisher: Springer; 1 edition (January 2007)
* Language: English
* ISBN-10: 1402054912
* ISBN-13: 978-1402054914

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Microbiology & Immunology Board Review Series

Microbiology & Immunology Board Review Series

By Arthur G Johnson, Arthur G. Johnson
Publisher: Lippincott Williams & Wilkins
Number Of Pages: 302
Publication Date: 2001-12-15
ISBN-10 / ASIN: 0781727707
ISBN-13 / EAN: 9780781727709
Binding: Paperback
Book Description:

BRS Microbiology and Immunology is a popular volume in the Board Review Series for medical students. Written in a concise, flexible, outline format, this book is intended to cover topics most commonly tested on USMLE. Included are 300 to 500 review questions in the USMLE-style format, and a comprehensive examination. New to the revised Fourth Edition are completely updated content; questions written in vignette format; a page of color plates depicting staining methods; and more information on immunology, parasitology, and fungi.

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Advanced Techniques in Diagnostic Microbiology

Advanced Techniques in Diagnostic Microbiology
By

• Publisher: Springer


• Number Of Pages: 540


• Publication Date: 2006-06-16


• Sales Rank: 963826


• ISBN / ASIN: 0387297413


• EAN: 9780387297415


• Binding: Hardcover


• Manufacturer: Springer


• Studio: Springer


• Average Rating: 0


• Total Reviews: 0

Book Description:

Clinical microbiologists are engaged in the field of diagnostic microbiology to determine whether pathogenic microorganisms are present in clinical specimens collected from patients with suspected infections. If microorganisms are found, these are identified and susceptibility profiles, when indicated, are determined. During the past two decades, technical advances in the field of diagnostic microbiology have made constant and enormous progress in various areas, including bacteriology, mycology, mycobacteriology, parasitology, and virology. The diagnostic capabilities of modern clinical microbiology laboratories have improved rapidly and have expanded greatly due to a technological revolution in molecular aspects of microbiology and immunology. In particular, rapid techniques for nucleic acid amplification and characterization combined with automation and user-friendly software have significantly broadened the diagnostic arsenal for the clinical microbiologist. The conventional diagnostic model for clinical microbiology has been labor-intensive and frequently required days to weeks before test results were available. Moreover, due to the complexity and length of such testing, this service was usually directed at the hospitalized patient population. The physical structure of laboratories, staffing patterns, workflow, and turnaround time all have been influenced profoundly by these technical advances. Such changes will undoubtedly continue and lead the field of diagnostic microbiology inevitably to a truly modern discipline. Advanced Techniques in Diagnostic Microbiology provides a comprehensive and up-to-date description of advanced methods that have evolved for the diagnosis of infectious diseases in the routine clinical microbiology laboratory. The book is divided into two sections. The first techniques section covers the principles and characteristics of techniques ranging from rapid antigen testing, to advanced antibody detection, to in vitro nucleic acid amplification techniques, and to nucleic acid microarray and mass spectrometry. Sufficient space is assigned to cover different nucleic acid amplification formats that are currently being used widely in the diagnostic microbiology field. Within each technique, examples are given regarding its application in the diagnostic field. Commercial product information, if available, is introduced with commentary in each chapter. If several test formats are available for a technique, objective comparisons are given to illustrate the contrasts of their advantages and disadvantages. The second applications section provides practical examples of application of these advanced techniques in several "hot" spots in the diagnostic field. A diverse team of authors presents authoritative and comprehensive information on sequence-based bacterial identification, blood and blood product screening, molecular diagnosis of ually transmitted diseases, advances in mycobacterial diagnosis, novel and rapid emerging microorganism detection and genotyping, and future directions in the diagnostic microbiology field. We hope our readers like this technique-based approach and your feedback is highly appreciated. We want to thank the authors who devoted their time and efforts to produce their chapters. We also thank the staff at Springer Press, especially Melissa Ramondetta, who initiated the whole project. Finally, we greatly appreciate the constant encouragement of our family members through this long effort. Without their unwavering faith and full support, we would never have had the courage to commence this project.

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Advances in Immunology

Advances in Immunology, Volume 95 (Advances in Immunology) (Advances in Immunology)
By

• Publisher: Academic Press


• Number Of Pages: 256


• Publication Date: 2007-08-31


• Sales Rank:


• ISBN / ASIN: 0123737087


• EAN: 9780123737083


• Binding: Hardcover


• Manufacturer: Academic Press


• Studio: Academic Press


• Average Rating: 0


• Total Reviews: 0

Book Description:

Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

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Microbiology: PreTest Self-Assessment and Review

Microbiology: PreTest Self-Assessment and Review

By Richard C. Tilton


Publisher: McGraw-Hill/Appleton & Lange
Number Of Pages: 220
Publication Date: 2001-08-06
Sales Rank: 877487
ISBN / ASIN: 0071374957
EAN: 9780071374958
Binding: Paperback
Manufacturer: McGraw-Hill/Appleton & Lange
Studio: McGraw-Hill/Appleton & Lange
Average Rating: 0
Total Reviews: 0


Book Description:

Gives medical students 500 questions, answers, and explanations to prepare for the microbiology section of the USMLE Step 1. The new edition includes many new questions in the two-step clinical format to simulate the USMLE Step 1.



Download Description:

These "500 questions, answers, and explanation" books are designed to simulate the United States Medical Licensing Examination (USMLE) Step 1. Each is authored by an expert in the field and has been reviewed by students who have recently passed the exam. As Step 1 is becoming increasingly more clinical in nature, when applicable, clinical vignette-style questions requiring a two-step reasoning process are also included. All of the Pretest titles include a "high-yield" fact section to

Table of Contents

High-Yield Facts; High-Yield Facts in Microbiology; Virology; Questions; Answers; Bacteriology; Questions; Answers; Physiology and Molecular Microbiology; Questions; Answers; Rickettsiae, Chlamydiae, and Mycoplasmas; Questions; Answers;
Mycology; Questions; Answers; Parasitology; Questions; Answers; Immunology; Questions; Answers; Bibliography; Index.

reinforce key concepts.

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Methods in Microbiology, Volume 31: Molecular Cellular Microbiology

Methods in Microbiology, Volume 31: Molecular Cellular Microbiology

(METHODS IN MOLECULAR BIOLOGY (PAPERBACK/SPIRAL))
By


Publisher: Academic Press
Number Of Pages: 612
Publication Date: 2002-02
Sales Rank: 2887825
ISBN / ASIN: 0126190712
EAN: 9780126190717
Binding: Plastic Comb
Manufacturer: Academic Press
Studio: Academic Press
Average Rating: 0
Total Reviews: 0



--------------------------------------------------------------------------------

Book Description:

This volume in the Methods in Microbiology series focuses on the interaction of microorganisms and the host cell, presenting detailed experimental techniques for modern microbiological research. The book focuses on current technical methods including imaging technologies, cellular biochemistry, and the establishment and exploitation of cell assay systems. Also covered are methods for studying gene expression and detecting virulence genes. By studying the major techniques used to study cross talks between microbes and cells, rather than just presenting systems, this book distinguishes itself as an essential guide for all researchers working in microbiology, cell biology, and immunology.

Key Features
* Focuses on current technical methods, including imaging technologies, cellular biochemistry, establishment and exploitation of cell assay systems
* Covers promising new areas such as global analysis of genome expression and proteomic analysis of cellular components.
* Encompasses the most recent and innovative techniques such as microarrays, new experimental models of infection and new cell assay systems
* Provides a large array of models covering the various strategies used by pathogens to infect their host
* Includes all current methods developed to study gene expression and detect virulence genes.

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In Silico Immunology

In Silico Immunology

• Publisher: Springer


• Number Of Pages: 451


• Publication Date: 2006-12-01


• Sales Rank:


• ISBN / ASIN: 0387392386


• EAN: 9780387392387


• Binding: Hardcover


• Manufacturer: Springer


• Studio: Springer


• Average Rating:


• Total Reviews:

Book Description:

Theoretical immunology is the application of mathematical modeling to diverse aspects of immunology. Immunoinformatics, the application of computational informatics to the study of immunological macromolecules, addresses questions in immunobiology and vaccinology, as well as addressing issues of data management, and can design and implement new experimental strategies. Artificial Immune Systems (AIS) uses ideas and concepts from immunology to guide and inspire new algorithms, data structures, and software development.
These three different disciplines are now poised to engineer a paradigm shift from hypothesis- to data-driven research, with new understanding emerging from the analysis of complex datasets: theoretical immunology, immunoinformatics, and Artificial Immune Systems (AIS). "in silico Immunology" will summarize these emergent disciplines and will address the issue of synergy as it shows how these three are set to transform immunological science and the future of health care.
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Seasonal Patterns of Stress, Immune Function, and Disease

Seasonal Patterns of Stress, Immune Function, and Disease


By Randy J. Nelson, Gregory E. Demas, Sabra L. Klein, Lance J. Kriegsfeld,
Publisher: Cambridge University Press
Number Of Pages: 308
Publication Date: 2002-03-25
Sales Rank: 1954059
ISBN / ASIN: 052159068X
EAN: 9780521590686
Binding: Hardcover
Manufacturer: Cambridge University Press
Studio: Cambridge University Press

This volume presents evidence that infection is cyclical with the seasons, and that this phenomenon is mirrored in cycles of immune function. The authors identify the mechanisms by which immune systems are bolstered to counteract seasonally-recurrent read.freeduan.com stressors, such as extreme temperature reductions and food shortages. Stress, infectious diseases, autoimmune diseases, and human cancers are examined, and the role of hormones such as melatonin and glucocorticoids are considered. This is the first monograph to examine seasonal immune function from an interdisciplinary perspective.

Download Description:
This book presents evidence that infection is cyclical with the seasons, and that this phenomenon is mirrored in cycles of immune function. The book identifies the mechanisms by which immune systems are bolstered to counteract seasonally-recurrent stressors, such as extreme temperature reductions and food shortages. Stress, infectious diseases, autoimmune diseases, and human cancers are examined, and the role of hormones such as melatonin and glucocorticoids is considered. The book begins with an overview of seasonality, biological rhythms and photoperiodism, and basic immunology, and then discusses seasonal fluctuations in disease prevalence, immune function, and energetics and endocrinology as they relate to immune function. The clinical significance of this issue is also addressed, as such seasonal changes may play an important role in the development and treatment of infections. This first monograph to examine seasonal immune function from an interdisciplinary perspective will serve practitioners as well as advanced undergraduates and graduate students in biology, immunology, human and veterinary medicine, neuroscience, endocrinology, and zoology.

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Tumor Immunology and Cancer Vaccines (Cancer Treatment and Research)

Tumor Immunology and Cancer Vaccines (Cancer Treatment and Research)


Publisher: Springer
Number Of Pages: 398
Publication Date: 2005-01-10
Sales Rank: 365327
ISBN / ASIN: 1402081197
EAN: 9781402081194
Binding: Hardcover
Manufacturer: Springer
Studio: Springer

Tumor Immunology and Cancer Vaccines addresses the state of the art knowledge of tumor immunology relevant to cancer vaccine and the different aspects of cancer vaccine development, covering the field from its basic science logic to clinical trials. The four sections of the book, Basic Tumor Immunology; Cancer Vaccine Development; Vaccine-Enhancing Strategies; and Clinical Trials Design, provide a general overview of the field, historic background, and the fields promises and problems.

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Medical Microbiology & Immunology

Medical Microbiology & Immunology

pages: 644 pages
Publisher: McGraw-Hill/Appleton & Lange
ISBN: 0071431993
Average Customer Review: Based on 3 review(s).
Format: DjVu
Size: 15.6 Mb Approx
Supplier: Amazon
Summary:
The most concise, comprehensive, and up-to-date medical microbiology immunology review! Gives students the high-yield information they need to prepare for the USMLE Step 1 and course exams. Completely updated throughout, the new edition covers developments in HIV, hepatitis, smallpox, SARS, and more. Features case discussions, USMLE-style questions, and a USMLE-style practice exam.

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Dictionary of Parasitology

Dictionary of Parasitology
Author: Peter J. Gosling

Product Details
pages: 408 pages
Publisher: CRC
ISBN: 0415308550
Format: PDF
Size: 5.94MB
Thanks to: grandmastero
Summary:

The Dictionary of Parasitology reflects current practice in all aspects of parasitology and includes spellings, punctuation, abbreviations, acronyms, symbols, nomenclature, prefixes, and suffixes. It assigns entries to the primary divisions of parasitology: human, veterinary, plant, insect, or fish. Including more than 11,500 entries, often with referral to related terms, as well as a wealth of other relevant information, this work provides the depth of knowledge that makes it an informative and useful volume for beginners and experts, as well as for writers and editors of scientific texts. Entries cover control measures, immunology, physiology, pharmacology, etc



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Updates in Diagnostic Pathology

Updates in Diagnostic Pathology

Publisher: Springer
Number Of Pages: 200
Publication Date: 2005-12-16
Sales Rank: 3063406
ISBN / ASIN: 0387253572
EAN: 9780387253572
Binding: Hardcover
Book Description:

Updates in Pathology provides pathologists, immunologists and pathologists/immunologists-in-training with a current view of basic pathology and immunology and its subdivisions, as well as topics in basic science, research and technology associated with pathology and immunology on all levels. Also discussed are the most recent advances in mechanisms of disease, new procedures and techniques of diagnostic pathology and immunology, and advancements and changes that have occurred in the last decade.

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The Allergy Report (Volumes 1-3

The Allergy Report (Volumes 1-3

Publisher: American Academy of Allergy, Asthma & Immunology
Number Of Pages:
Publication Date: 2000
Sales Rank: 1655896
ISBN / ASIN: 0000008788
EAN: 9780000008787
Binding: Hardcover
Manufacturer: American Academy of Allergy, Asthma & Immunology

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Molecular Mechanisms of Basal Cell and Squamous Cell Carcinomas

Molecular Mechanisms of Basal Cell and Squamous Cell Carcinomas

By
Publisher: Springer
Number Of Pages: 137
Publication Date: 2006-04-26
Sales Rank: 2953752
ISBN / ASIN: 0387260463
EAN: 9780387260464
Binding: Hardcover
Book Description:

This book provides a comprehensive, highly readable overview of our current knowledge of the molecular pathology of basal cell and squamous cell carcinomas. The chapters present the newest findings in epidemiology, photocarcinogenesis, genetics, immunology and molecular pathology of these epithelial skin tumours. Topics include the importance of the hedgehog/patched/smoothened/GLI, p53, PDGF, or TGF-b signalling pathways as well as the relevance of papilloma virus infections, apoptosis, DNA-repair and telomerase.

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Immunology

Practical Immunology

Product Details
Book Publisher: Blackwell Publishing Limited (01 December, 2001)
ISBN: 0865429618
Book author: Frank C. Hay, Olwyn M. R. Westwood, Paul N. Nelson, Leslie Hudson
Amazon Rating:

Book Description:
Practical Immunology is a basic text aimed at immunology students and researchers at all levels who need a comprehensive overview of the methodology of immunology. The rapid and startling innovations in immunology over the past two decades have their root in sound experimental practice and it has always been the aim of this book to educate researchers in the design and performance of complex techniques. It will appeal to students of immunlogy, graduate students embarking on bench science, or specialized immunologists who need to use an immunological technique outside their sphere of expertise. The book gives straightforward descriptions of the most common techniques that are referred to, but not always well explained, in the current literature. Tips for improving the techniques, troubleshooting and other handy bits of advice make it more than just a book of standard protocols. Where possible, the techniques are explained in such a way that the purchase of specialist kits is avoidable. For those who are a little rusty on their basic immunology the book also gives background information, making it the only one stop shop around. Practical Immunology tells you how to do the basic techniques that form the anatomy of experimental immunology. This latest edition has been fully revised to include the basic techniques of molecular biology, with a revised section on cytokines, an expanded section on clinical immunology and new techniques in epitope mapping and the study of cell adhersion molecules.

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Color Atlas of Immunology

ISBN: 0865779643
Title: Color Atlas of Immunology (Thieme Flexibook)
Author: Gerd-Rudiger Burmester
Publisher: Thieme Medical Publishers


Summary:
Book Description
provides all the basics of immunology in a convenient, easy-to-read format...explains the interactions between the fundamental principles of immunology and its clinical applications, with more than 130 high-quality color plates to illustrate the concepts described in the text

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